Abstract

For patients with chronic liver disease, receiving a transplant is the only lasting option for treatment. However, few patients receive transplants from viable human donors due to limited availability. Additionally, various challenges are posed when conducting hepatocyte research, specifically in isolating quality human hepatocytes for reliable, consistent pharmaceutical testing.By developing a consistent, high-quality line of pig cells, Cytotheryx can provide an alternative option for pharmaceutical testing. In the future, the cloned pigs could serve as potential bio-incubators to support human liver cell expansion and regeneration. At this stage of research, the main objective is to determine metabolic consistency in Cytotheryx pig liver cells. By comparing the metabolic profiles ofpig and human liver cells, we can determine their similarities in function and evaluate their efficacy for research purposes.

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Apr 3rd, 11:00 AM Apr 3rd, 1:00 PM

Porcine vs Human Hepatocyte Metabolic Characterization

For patients with chronic liver disease, receiving a transplant is the only lasting option for treatment. However, few patients receive transplants from viable human donors due to limited availability. Additionally, various challenges are posed when conducting hepatocyte research, specifically in isolating quality human hepatocytes for reliable, consistent pharmaceutical testing.By developing a consistent, high-quality line of pig cells, Cytotheryx can provide an alternative option for pharmaceutical testing. In the future, the cloned pigs could serve as potential bio-incubators to support human liver cell expansion and regeneration. At this stage of research, the main objective is to determine metabolic consistency in Cytotheryx pig liver cells. By comparing the metabolic profiles ofpig and human liver cells, we can determine their similarities in function and evaluate their efficacy for research purposes.

 

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