Abstract

Alzheimer’s is a very prevalent disease that has no true dependable and effective treatment. Through research and trials melatonin has been seen as a potential therapeutic option for both structural and behavioral changes in Alzheimer’s. Studies have shown low levels of natural melatonin in CSF are a strong indicator of Alzheimer's Disease. This suggests melatonin could be used as a prophylactic measure as well as a treatment for slowing the disease’s neuropathological changes. Results showed that melatonin improves circadian rhythm and sleep quality leading to more effective glymphatic clearing of free radicals, improving cognition, and decreasing behavioral disturbances.

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Apr 11th, 11:00 AM Apr 11th, 1:00 PM

Melatonin as Treatment and Prophylaxis for Alzheimer's Disease

Alzheimer’s is a very prevalent disease that has no true dependable and effective treatment. Through research and trials melatonin has been seen as a potential therapeutic option for both structural and behavioral changes in Alzheimer’s. Studies have shown low levels of natural melatonin in CSF are a strong indicator of Alzheimer's Disease. This suggests melatonin could be used as a prophylactic measure as well as a treatment for slowing the disease’s neuropathological changes. Results showed that melatonin improves circadian rhythm and sleep quality leading to more effective glymphatic clearing of free radicals, improving cognition, and decreasing behavioral disturbances.

 

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