Abstract
Meniscal injuries are a common result of trauma to the knee. The main two surgical treatments available are partial meniscectomy or full meniscectomy due to the lack of blood flow in that region. These two treatments cause long-term complications such as pain, lack of mobility, and/or osteoarthritis.
To avoid these complications, researchers have looked at placing collagen meniscal implantations (CMI) into the knee. The collagen implantation is composed of type I collagen from bovine Achilles tendon and was infused with glycosaminoglycans (GAGs) to trigger cellular growth. Patients were grouped into cohorts based on tears in the lateral or medial meniscus that underwent a partial or full meniscectomy. Following the procedure, patients were evaluated based on Tegner scale, Lysholm Score, IKDC, and MRI outcomes. These patients were then reevaluated at two years, five years, and ten years.
The implantation had a 90% survival rate at ten years. CMI has proved to be a practical possibility for patients who have had a partial or full meniscectomy due to the regenerative qualities and reduced deterioration of the knee itself. The research showed that there were significant improvements in quality of life and long-term outcomes. This is a practical option for patients that live an active lifestyle or occupations that require adequate range of motion.
Included in
Collagen Meniscal Implantation Outcomes Following Partial and Full Meniscectomies
Meniscal injuries are a common result of trauma to the knee. The main two surgical treatments available are partial meniscectomy or full meniscectomy due to the lack of blood flow in that region. These two treatments cause long-term complications such as pain, lack of mobility, and/or osteoarthritis.
To avoid these complications, researchers have looked at placing collagen meniscal implantations (CMI) into the knee. The collagen implantation is composed of type I collagen from bovine Achilles tendon and was infused with glycosaminoglycans (GAGs) to trigger cellular growth. Patients were grouped into cohorts based on tears in the lateral or medial meniscus that underwent a partial or full meniscectomy. Following the procedure, patients were evaluated based on Tegner scale, Lysholm Score, IKDC, and MRI outcomes. These patients were then reevaluated at two years, five years, and ten years.
The implantation had a 90% survival rate at ten years. CMI has proved to be a practical possibility for patients who have had a partial or full meniscectomy due to the regenerative qualities and reduced deterioration of the knee itself. The research showed that there were significant improvements in quality of life and long-term outcomes. This is a practical option for patients that live an active lifestyle or occupations that require adequate range of motion.