Abstract

Mycobacteriophages are viruses that infect mycobacteria; little is known about their cis-regulatory transcriptional control elements. In previous work, we identified and characterized a regulatory region (40,670- 40,951 bp) in JacoRen57, an AB cluster mycobacteriophage. The regulatory region appears to play a role in regulating the expression of Gene 50. Utilizing qRT-PCR, we investigated further to see if Gene 50 mRNA is produced during an active infection of Mycobacterium smegmatis by JacoRen57.

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Apr 20th, 11:00 AM Apr 20th, 1:00 PM

mRNA Production of Gene 50 in JacoRen57

Mycobacteriophages are viruses that infect mycobacteria; little is known about their cis-regulatory transcriptional control elements. In previous work, we identified and characterized a regulatory region (40,670- 40,951 bp) in JacoRen57, an AB cluster mycobacteriophage. The regulatory region appears to play a role in regulating the expression of Gene 50. Utilizing qRT-PCR, we investigated further to see if Gene 50 mRNA is produced during an active infection of Mycobacterium smegmatis by JacoRen57.

 

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