This literature review explores trauma and trauma-informed practices. This literature review uses scholarly articles and journals explains an overview of trauma, toxic stress on brain development, assumptions of trauma-informed approaches, trauma screening and assessment, and an examination of teacher’s personal anxiety. The research will show how prevalent trauma is and negative impacts trauma has on students and adults. Trauma can cause a lot of difficulties on academic achievement for students. This literature review also includes information of protective factors such as resiliency, attachment, relaxation techniques, collaboration among professionals, instruction on expressing feelings, play in the classroom, and classroom environment suggestions. Studies show how important these protective factors are to reduce the negative impacts of trauma. This literature review concludes with practical applications of ways teachers can include trauma-informed practices in the classroom to combat the negative impacts trauma has on students.